Description
Buy Thymosin Beta 4 2mg (TB-500) for Laboratory Research with Discreet Worldwide Shipping
Thymosin Beta 4 2mg (TB-500) is a peptide research material associated with research into cellular migration, angiogenesis, cytoskeletal regulation, inflammation and tissue-repair processes.
Thymosin β4 (Tβ4) is a naturally occurring peptide involved in cellular biology, particularly through its interaction with actin. Research has associated Tβ4 with processes including cell migration, angiogenesis, inflammatory signaling and tissue remodeling.
The name TB-500, however, requires additional care. The FDA substance database identifies TB-500 as an N-terminally acetylated 17–23 fragment of thymosin β4, with the sequence LKKTETQ, rather than simply treating TB-500 as synonymous with the complete thymosin β4 molecule.
For this reason, ChemDirect should identify the exact peptide supplied by the applicable batch documentation and avoid suggesting that all products sold under the names “Thymosin Beta 4” and “TB-500” are chemically identical.
What Is Thymosin Beta 4 2mg (TB-500)?
Thymosin β4 is a naturally occurring peptide that has been extensively studied in cellular and tissue biology. It is particularly known for its ability to bind actin and influence cellular processes associated with migration and cytoskeletal organization.
TB-500 is a related peptide designation. According to the FDA’s Substance Registration System, TB-500 corresponds to the N-terminally acetylated 17–23 fragment of thymosin β4, with the sequence LKKTETQ.
Basic Product Profile
| Property | Standard Information |
|---|---|
| Product Name | Thymosin Beta 4 2mg (TB-500) |
| Quantity | 2mg |
| Product Category | Research Peptide |
| Research Area | Cellular and tissue biology |
| Common TB-500 Sequence | LKKTETQ |
| TB-500 Chemical Description | N-terminally acetylated 17–23 fragment of thymosin β4 |
| TB-500 CAS | 885340-08-9 |
| TB-500 Estimated Molecular Formula | C36H66N10O13 |
| TB-500 Estimated Molecular Weight | 846.981 Da |
| Physical Form | Typically lyophilized research peptide |
| Purity | Batch-specific COA |
| Intended Use | Laboratory research only |
The TB-500 sequence, CAS number and estimated molecular characteristics are listed in the FDA’s substance database.
How Does Thymosin Beta 4 / TB-500 Work in Biological Research?
Thymosin β4 is particularly notable for its interaction with G-actin, a central component of the cellular cytoskeleton.
Research describes Tβ4 as an actin-sequestering peptide that can influence the balance between actin polymerization and depolymerization. This relationship helps explain its investigation in cellular migration, development and tissue-response research.
Actin and Cytoskeletal Research
Tβ4 binds G-actin and can influence actin dynamics within cells.
Cell Migration
The peptide has been investigated in relation to cellular migration, an important process in tissue remodeling.
Angiogenesis Research
Research has investigated Tβ4 in relation to blood-vessel formation and endothelial responses.
Inflammation Research
Experimental studies have examined relationships between Tβ4 and inflammatory pathways.
Tissue Biology
The peptide has been studied in experimental models involving wound, vascular, ocular and other tissue responses. A 2026 scoping review found that most of the published evidence remains preclinical and that direct TB-500 evidence is considerably more limited than the literature on Tβ4.
Key Research Characteristics of Thymosin Beta 4 / TB-500
Cellular Migration
Tβ4 has been associated with cellular migration and cytoskeletal activity.
Angiogenesis
Experimental research has investigated Tβ4 in vascular and endothelial models.
Tissue-Response Research
Studies have examined its involvement in experimental wound and tissue-repair processes.
Cytoskeletal Biology
Its relationship with actin makes it useful for investigating cellular structure and movement.
Regenerative Biology
Tβ4 has been investigated in experimental regeneration models, although the strength of evidence varies substantially between applications.
Product Details and Purity
The 2mg product should be described according to the exact material supplied by ChemDirect’s manufacturer.
If the product is specifically TB-500, the FDA database identifies the substance as an N-terminally acetylated fragment with the sequence LKKTETQ and an estimated molecular weight of 846.981 Da.
If ChemDirect’s supplier instead provides full-length thymosin β4, the product specifications should be different.
Thymosin Beta 4 2mg (TB-500) Specifications
| Specification | Details |
|---|---|
| Product | Thymosin Beta 4 2mg (TB-500) |
| Quantity | 2mg |
| Product Category | Research Peptide |
| TB-500 Sequence | LKKTETQ |
| Modification | N-terminal acetylation |
| Peptide Classification | Thymosin β4-related peptide fragment |
| CAS | 885340-08-9 |
| Estimated Formula | C36H66N10O13 |
| Estimated Molecular Weight | 846.981 Da |
| Physical Form | Typically lyophilized powder |
| Appearance | Typically white to off-white |
| Purity | Batch-specific COA |
| Identity Testing | LC-MS where performed |
| Purity Testing | HPLC where performed |
| Intended Use | Laboratory research |
| Documentation | COA/SDS where available |
Potential Applications — For Research Use Only
TB4 and TB-500-related materials have been investigated across several scientific areas.
Cellular Biology
Research into cytoskeletal organization, cellular movement and cell signaling.
Vascular Research
Studies investigating angiogenesis and endothelial responses.
Wound Biology
Experimental studies examining wound and tissue responses.
Musculoskeletal Research
TB4/TB-500 has attracted substantial interest in musculoskeletal research, although a 2026 review found that direct human evidence for musculoskeletal applications remains limited.
Ocular Research
Thymosin β4 has been studied in experimental and clinical research involving ocular and corneal applications.
Regenerative Biology
Research has explored Tβ4 in multiple tissue-repair and regeneration models.
These are research areas and should not be presented as approved medical indications
Research Handling and Storage
The exact storage requirements should be taken from the manufacturer’s documentation for the specific batch.
Dosage & Usage Guidelines
by manufacturer guided which will be in the package sent
Safety, Side Effects & Precautions
TB4 and TB-500 should be treated as research materials rather than consumer medicines.
Researchers should:
- Review the applicable SDS before handling.
- Follow appropriate laboratory PPE requirements.
- Avoid contamination.
- Maintain appropriate storage conditions.
- Keep batch documentation.
- Follow institutional safety procedures.
- Dispose of research materials according to applicable laboratory requirements.
For laboratory research purposes only. Not intended for human consumption, self-administration, diagnosis, treatment or prevention of disease.
Quality Assurance & Testing
Peptide Identity
Appropriate analytical techniques such as mass spectrometry can be used to confirm peptide identity where performed.
Purity Testing
HPLC or an equivalent validated method may be used to evaluate peptide purity.
Batch Testing
Batch-specific testing provides stronger product information than generic purity claims.
Accurate TB-500 Identification
Because TB-500 and full-length thymosin β4 are frequently conflated in commercial descriptions, ChemDirect should clearly identify the actual peptide supplied. The 2026 scoping review specifically notes variability in commercial use of the term TB-500.
Commitment to Quality and Compliance
ChemDirect emphasize on:
- Accurate product identification
- Transparent peptide specifications
- Batch traceability
- Analytical documentation
- COA/SDS availability where applicable
- Appropriate research-use labeling
- Responsible sourcing
- Secure packaging
Why Choose ChemDirect for Thymosin Beta 4 2mg (TB-500)?
Research-Focused Product
The product is positioned for laboratory and scientific research.
Clearly Identified Material
ChemDirect can distinguish the TB-500 fragment from full-length thymosin β4.
Transparent Specifications
Researchers can review the quantity, peptide identity and available analytical information.
Batch Documentation
COA information can provide batch-specific evidence of identity and purity.
Secure Packaging
Research materials should be packaged appropriately for transportation.
Customer Support
ChemDirect can provide product and documentation assistance.
Shipping & Delivery Information
Order Processing
Orders are processed according to ChemDirect’s current fulfillment schedule.
Packaging
The product should be securely packaged to protect the research material during transportation.
Discreet Packaging
Where offered, discreet external packaging can be used.
International Shipping
International availability depends on destination-specific regulations and import requirements.
Tracking
Tracking information is provided where supported by the shipping method.
How to Order Thymosin Beta 4 2mg (TB-500) Online
Step 1: Review the product information.
Step 2: Confirm the exact peptide identity and form.
Step 3: Select the 2mg quantity.
Step 4: Add the product to your cart.
Step 5: Complete checkout.
Step 6: Confirm your order details.
Step 7: Track the shipment when tracking is available.
Frequently Asked Questions
What is Thymosin Beta 4?
Thymosin β4 is a naturally occurring peptide that has been extensively studied for its involvement in actin regulation, cellular migration, angiogenesis and tissue biology.
What is TB-500?
The FDA substance database identifies TB-500 as the N-terminally acetylated 17–23 fragment of thymosin β4, with the sequence LKKTETQ.
Is TB-500 the same as full-length Thymosin Beta 4?
Not necessarily. The terms are often used interchangeably in commercial peptide discussions, but chemically they can refer to different materials. The FDA database specifically identifies TB-500 as the LKKTETQ fragment.
What is the sequence of TB-500?
The FDA database lists the TB-500 sequence as LKKTETQ, with N-terminal acetylation.
What is the molecular weight of TB-500?
The FDA database lists an estimated molecular weight of 846.981 Da for TB-500.
What is the CAS number of TB-500?
The FDA database lists CAS 885340-08-9.
What is TB-500 researched for?
TB4/TB-500-related research includes cellular migration, angiogenesis, tissue biology and musculoskeletal research. However, the 2026 evidence review found that most research concerns full-length TB4 and that direct TB-500 evidence remains limited.
Does TB-500 have human research?
There is human research involving thymosin β4, including a Phase I study of recombinant human Tβ4, but that should not automatically be interpreted as evidence for commercial TB-500 products.
What purity does ChemDirect TB-500 have?
The exact purity should be taken from the batch-specific COA.
How should TB-500 be stored?
Follow the manufacturer’s storage instructions for the specific batch and formulation.
Is TB-500 intended for human use?
The ChemDirect research product should be clearly labeled according to its actual regulatory status and intended use. For a research product, use laboratory research only language.
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- CJC-1295 MOD GRF 1-29 Without DAC 2mg
- Beta-Amyloid (1-40), Y10W Mutant
- Other research peptides
- Related laboratory research materials
Final Thoughts
Thymosin β4 and TB-500 are closely related research topics, but they should not automatically be treated as chemically identical. Thymosin β4 is a naturally occurring peptide involved in actin regulation and several cellular processes, while the FDA’s substance database identifies TB-500 specifically as the N-terminally acetylated LKKTETQ fragment of thymosin β4.
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